CASE STUDY

Academia: Optimize and validate research protocols with mAb drug aliquots

“Evidentic was the only source that offered small aliquots of original therapeutic mAbs at an affordable price range. The aliquots came in an easy-to-use-and-store format that was apt for my research purpose.”
Ivanna Hrynchak
PhD Student, ICNAS, Universidade d Coimbra, Portugal
ICNAS is a medical imaging research institution of the University of Coimbra that congregates the main medical imaging modalities (PET, MRI, CT, EEG) in the same building, including cyclotron and radiochemistry facilities. The following is an edited excerpt of the interview with Ivanna Hrynchak, doctoral student at ICNAS-Produção conducted on 24th November 2020.

What makes therapeutic mAbs an essential part of your doctoral program?

The objective of my research is to synthesize a radiolabelled antibody against HER2 for non-invasive imaging and therapeutic purposes. Trastuzumab is utilized for this purpose because of its affinity for the HER2 receptor. Hence, trastuzumab is used for the optimization of reaction conditions and subsequent purification. In order to evaluate the therapeutic efficacy of radiolabelled trastuzumab in vitro and in vivo models, the mAB used must be classified as an Active Pharmaceutical Ingredient (API).

What challenges did you face in finding Therapeutic anti-HER2 antibodies?

Several companies sell mAbs. However, I required an approved therapeutic mAb for my reaction optimization and quality control. I had very limited choices and it was difficult to find good deals which were cost effective and offered an ideal pack size.

How did Evidentic services help with the progress in your research?

Evidentic offered me the best quote in regards to quantity and price. Therapeutic mAbs from Evidentic are available in aliquots which facilitates easy-to-use format and storage. The process from placing an order to the arrival of the product at my lab was fulfilled in approximately 3 working days. This helped in speeding up my research timelines.

What was your overall experience with Evidentic?

I received premium quality therapeutic mAbs at an affordable price that was shipped within a very short time. I also appreciate the excellent customer service as Evidentic helped with all the product related queries.

Thank you very much, Ivanna, for taking the time for this interview.

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