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Romiplostim

Therapeutic Romiplostim fusion protein from the original Nplate® commercial drug.

Reference Standard as Aliquots

Nplate®
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Abatacept ABS2028
2023.02
Orencia®
LT
44,60 € /mg
Select quantity:
Max: 50
Min: 10
Step: 5
Max: 50
Min: 10
Step: 5
mg
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Adalimumab 54371XH03
2025.05
Humira®
DE
112,50 € /mg
Max: 4
Min: 1
Step: 1
mg
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Adalimumab 70225XH07
2018.09
Humira®
DE
113,00 € /mg
Select quantity:
Max: 16
Min: 4
Step: 4
Max: 16
Min: 4
Step: 4
mg
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Adalimumab 73254XH03
2018.12
Humira®
LV
113,00 € /mg
Select quantity:
Max: 40
Min: 4
Step: 4
Max: 40
Min: 4
Step: 4
mg
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Adalimumab 76287XH07
2019.03
Humira®
DE
113,00 € /mg
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Max: 40
Min: 4
Step: 4
Max: 40
Min: 4
Step: 4
mg
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Adalimumab 76287XH11
2019.03
Humira®
DE
113,00 € /mg
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Max: 20
Min: 4
Step: 4
Max: 20
Min: 4
Step: 4
mg
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Adalimumab 80315XH04
2019.07
Humira®
LV
113,00 € /mg
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Max: 32
Min: 4
Step: 4
Max: 32
Min: 4
Step: 4
mg
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Aflibercept
Date to be defined
Eylea®
DE
1.302,00 € /mg
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Max:
Min: 1
Step: 1
Max:
Min: 1
Step: 1
mg
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Albutrepenonacog Alfa P100349638
2023.01
Idelvion®
DE
20,80 € /mg
Select quantity:
Max: 125
Min: 25
Step: 25
Max: 125
Min: 25
Step: 25
mg
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Aldesleukin M001692
2024.07
Proleukin®
DE
347,00 € /mg
Select quantity:
Max: 3
Min: 1
Step: 1
Max: 3
Min: 1
Step: 1
mg
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Aldesleukin M003854
2026.01
Proleukin®
DE
260,00 €/mg
Max: 19
Min: 1
Step: 1
mg
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Alemtuzumab EW2474
2026.08
Lemtrada®
DE
1.862,00 €/mg
Max: 20
Min: 1
Step: 1
mg
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Alglucosidase alfa DW1451
2025.12
Myozyme®
DE
84,00 €/mg
Max: 315
Min: 1
Step: 1
mg
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Alirocumab
Date to be defined
Praluent®
DE
36,00 € /mg
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Max:
Min: 60
Step: 6
Max:
Min: 60
Step: 6
mg
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Alteplase 201958
2023.02
Actilyse®
DE
264,00 € /mg
Select quantity:
Max: 10
Min: 1
Step: 1
Max: 10
Min: 1
Step: 1
mg
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Amivantamab PES0C04
2027.04
Rybrevant®
DE
40,00 €/mg
Max: 50
Min: 1
Step: 1
mg
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Anifrolumab EAHK
2026.11
Saphnelo®
DE
333,00 € /mg
Select quantity:
Max: 41
Min: 1
Step: 1
Max: 41
Min: 1
Step: 1
mg
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Atezolizumab B0006B01
2022.03
Tecentriq®
LT
30,00 € /mg
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Max: 120
Min: 24
Step: 12
Max: 120
Min: 24
Step: 12
mg
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Avalglucosidase alfa CW3924
05/2026
Nexviadyme®
DE
1.099,00 € /mg
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Max: 18
Min: 1
Step: 1
Max: 18
Min: 1
Step: 1
mg
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Avelumab AU026497
2021.01
Bavencio®
DE
72,00 € /mg
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Max: 20
Min: 6
Step: 2
Max: 20
Min: 6
Step: 2
mg
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Belatacept 8028708
2025.01
Nulojix®
37,00 €/mg
Max: 180
Min: 1
Step: 1
mg
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Belimumab
Date to be defined
Benlysta®
DE
59,00 € /mg
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Max:
Min: 32
Step: 4
Max:
Min: 32
Step: 4
mg
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Benralizumab
Date to be defined
Fasenra®
DE
504,00 € /mg
Select quantity:
Max:
Min: 9
Step: 1
Max:
Min: 9
Step: 1
mg
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Bevacizumab B7219H04
2018.06
Avastin®
DE
106,00 € /mg
Select quantity:
Max: 20
Min: 4
Step: 2
Max: 20
Min: 4
Step: 2
mg
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Bevacizumab B7223H06
2018.09
Avastin®
DE
106,00 € /mg
Select quantity:
Max: 20
Min: 4
Step: 2
Max: 20
Min: 4
Step: 2
mg
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Bevacizumab B7223H17
2018.09
Avastin®
DE
106,00 € /mg
Select quantity:
Max: 20
Min: 4
Step: 2
Max: 20
Min: 4
Step: 2
mg
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Bevacizumab B7226H07
2018.12
Avastin®
DE
106,00 € /mg
Max: 20
Min: 4
Step: 2
mg
Add to list
Bevacizumab B7230H14
2019.03
Avastin®
DE
106,00 € /mg
Select quantity:
Max: 20
Min: 4
Step: 2
Max: 20
Min: 4
Step: 2
mg
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Bevacizumab B7234H02
2019.08
Avastin®
LV
106,00 € /mg
Select quantity:
Max: 20
Min: 4
Step: 2
Max: 20
Min: 4
Step: 2
mg
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Bevacizumab B8020H05
2019.10
Avastin®
DE
106,00 € /mg
Select quantity:
Max: 20
Min: 4
Step: 2
Max: 20
Min: 4
Step: 2
mg
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Bevacizumab B8800H28
2021.03
Avastin®
LT
106,00 € /mg
Select quantity:
Max: 12
Min: 4
Step: 2
Max: 12
Min: 4
Step: 2
mg
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Bevacizumab H0152B21
2017.09
Avastin®
DE
89,00 € /mg
Select quantity:
Max: 30
Min: 6
Step: 3
Max: 30
Min: 6
Step: 3
mg
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Bevacizumab H0156B21
2018.03
Avastin®
DE
89,00 € /mg
Select quantity:
Max: 30
Min: 6
Step: 3
Max: 30
Min: 6
Step: 3
mg
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Bevacizumab H0340H03
2024.07
Avastin®
LT
106,00 € /mg
Select quantity:
Max: 20
Min: 4
Step: 2
Max: 20
Min: 4
Step: 2
mg
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Bevacizumab H0403H07
2027.03
Avastin®
DE
212,00 € /mg
Select quantity:
Max: 41
Min: 1
Step: 1
Max: 41
Min: 1
Step: 1
mg
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Bezlotoxumab
Date to be defined
Zinplava®
DE
254,00 € /mg
Select quantity:
Max:
Min: 16
Step: 2
Max:
Min: 16
Step: 2
mg
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Bimekizumab
Date to be defined
Bimzelx®
DE
73,00 € /mg
Select quantity:
Max:
Min: 64
Step: 8
Max:
Min: 64
Step: 8
mg
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Blinatumomab 1164206A
2027.07
Blincyto®
CH
788,00 €/mg
Max: 8
Min: 1
Step: 1
mg
Add to list
Brentuximab vedotin 12710715
2027.09
Adcetris®
DE
370,00 €/mg
Max: 50
Min: 1
Step: 1
mg
Add to list
Brodalumab 1097025
2022.05
Kyntheum®
DE
42,14 € /mg
Select quantity:
Max: 70
Min: 14
Step: 7
Max: 70
Min: 14
Step: 7
mg
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Brolucizumab
Date to be defined
Beovu®
DE
276,00 € /mg
Select quantity:
Max:
Min: 9,9
Step: 3
Max:
Min: 9,9
Step: 3
mg
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Burosumab
Date to be defined
Crysvita®
DE
1.442,00 € /mg
Select quantity:
Max:
Min: 5
Step: 1
Max:
Min: 5
Step: 1
mg
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Canakinumab SHJR5
2025.07
Ilaris®
DE
1.884,00 €/mg
Max: 21
Min: 1
Step: 1
mg
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Canakinumab SHNU8
2025.07
Ilaris®
DE
1.884,00 €/mg
Max: 23
Min: 1
Step: 1
mg
Add to list
Cemiplimab
Date to be defined
Libtayo®
DE
118,00 € /mg
Select quantity:
Max:
Min: 50
Step: 5
Max:
Min: 50
Step: 5
mg
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Certolizumab Pegol 323535
2022.09
Cimzia®
DE
34,25 € /mg
Select quantity:
Max: 72
Min: 16
Step: 8
Max: 72
Min: 16
Step: 8
mg
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Certolizumab Pegol 378984
2025.03
Cimzia®
DE
26,00 €/mg
Max: 256
Min: 1
Step: 1
mg
Add to list
Cetuximab 212882
2019.11
Erbitux®
DE
98,50 € /mg
Select quantity:
Max: 20
Min: 6
Step: 2
Max: 20
Min: 6
Step: 2
mg
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Cetuximab 212884
2020.01
Erbitux®
DE
98,50 € /mg
Select quantity:
Max: 20
Min: 4
Step: 2
Max: 20
Min: 4
Step: 2
mg
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Cetuximab 238081
2021.05
Erbitux®
DE
98,50 € /mg
Select quantity:
Max: 20
Min: 4
Step: 2
Max: 20
Min: 4
Step: 2
mg
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Cetuximab 244682
2021.09
Erbitux®
DE
65,80 € /mg
Select quantity:
Max: 50
Min: 5
Step: 5
Max: 50
Min: 5
Step: 5
mg
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Cetuximab 248033
2021.11
Erbitux®
DE
98,50 € /mg
Select quantity:
Max: 20
Min: 4
Step: 2
Max: 20
Min: 4
Step: 2
mg
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Crizanlizumab
Date to be defined
Adakveo®
DE
167,00 € /mg
Select quantity:
Max:
Min: 18
Step: 2
Max:
Min: 18
Step: 2
mg
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Daratumumab DQF1105
2018.11
Darzalex®
DE
121,00 € /mg
Select quantity:
Max: 6
Min: 4
Step: 2
Max: 6
Min: 4
Step: 2
mg
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Daratumumab DQF1122
2019.05
Darzalex®
DE
121,00 € /mg
Select quantity:
Max: 34
Min: 4
Step: 4
Max: 34
Min: 4
Step: 4
mg
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Daratumumab DUL0200
2023.11
Darzalex®
DE
88,50 € /mg
Select quantity:
Max: 12
Min: 4
Step: 4
Max: 12
Min: 4
Step: 4
mg
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Daratumumab DVL1400
2024.11
Darzalex®
DE
88,50 € /mg
Select quantity:
Max: 40
Min: 4
Step: 4
Max: 40
Min: 4
Step: 4
mg
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Daratumumab GHS0702
2018.01
Darzalex®
DE
121,00 € /mg
Select quantity:
Max: 24
Min: 4
Step: 4
Max: 24
Min: 4
Step: 4
mg
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Daratumumab GKS0B06
2018.04
Darzalex®
DE
101,30 € /mg
Select quantity:
Max: 30
Min: 6
Step: 3
Max: 30
Min: 6
Step: 3
mg
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Daratumumab HIS4901
2019.09
Darzalex®
DE
121,00 € /mg
Select quantity:
Max: 20
Min: 4
Step: 2
Max: 20
Min: 4
Step: 2
mg
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Daratumumab JBS2Y23
2021.01
Darzalex®
DE
121,00 € /mg
Select quantity:
Max: 20
Min: 4
Step: 2
Max: 20
Min: 4
Step: 2
mg
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Daratumumab LHS2651
2023.07
Darzalex®
DE
121,00 € /mg
Select quantity:
Max: 20
Min: 4
Step: 2
Max: 20
Min: 4
Step: 2
mg
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Denosumab
Date to be defined
Xgeva®
DE
81,00 € /mg
Select quantity:
Max:
Min: 27
Step: 3
Max:
Min: 27
Step: 3
mg
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Denosumab 1078318B
2018.11
Prolia®
DE
108,00 € /mg
Select quantity:
Max: 12
Min: 3
Step: 3
Max: 12
Min: 3
Step: 3
mg
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Denosumab 1080147A
2019.07
Prolia®
DE
108,00 € /mg
Select quantity:
Max: 30
Min: 3
Step: 3
Max: 30
Min: 3
Step: 3
mg
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Denosumab 1082130A
2019.10
Prolia®
DE
108,00 € /mg
Select quantity:
Max: 15
Min: 3
Step: 3
Max: 15
Min: 3
Step: 3
mg
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Denosumab 1087971A
2020.04
Prolia®
DE
108,00 € /mg
Select quantity:
Max: 21
Min: 3
Step: 3
Max: 21
Min: 3
Step: 3
mg
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Denosumab 1090173B
2020.09
Prolia®
DE
108,00 € /mg
Select quantity:
Max: 6
Min: 3
Step: 3
Max: 6
Min: 3
Step: 3
mg
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Denosumab 1094444A
2021.01
Prolia®
DE
108,00 € /mg
Select quantity:
Max: 6
Min: 3
Step: 3
Max: 6
Min: 3
Step: 3
mg
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Denosumab 1114463
2022.06
Prolia®
DE
108,00 € /mg
Select quantity:
Max: 30
Min: 3
Step: 3
Max: 30
Min: 3
Step: 3
mg
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Denosumab 1115845
2022.10
Prolia®
DE
108,00 € /mg
Select quantity:
Max: 15
Min: 3
Step: 3
Max: 15
Min: 3
Step: 3
mg
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Dornase Alfa N0024B13
2023.12
Pulmozyme®
DE
188,00 € /mg
Select quantity:
Max: 3
Min: 1
Step: 1
Max: 3
Min: 1
Step: 1
mg
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Dostarlimab 1956746
2025.07
Jemperli®
DE
38,00 €/mg
Max: 500
Min: 1
Step: 1
mg
Add to list
Dostarlimab 1979426
2025.10
Jemperli®
IT
105,00 €/mg
Max: 430
Min: 1
Step: 1
mg
Add to list
Dostarlimab 1979430
2025.10
Jemperli®
CH
86,00 €/mg
Max: 430
Min: 1
Step: 1
mg
Add to list
Dostarlimab 1996533
2026.03
Jemperli®
USA
180,00 €/mg
Max: 430
Min: 1
Step: 1
mg
Add to list
Dulaglutide D490817
2023.07
Trulicity®
DE
319,00 € /mg
Select quantity:
Max: 10
Min: 1
Step: 1
Max: 10
Min: 1
Step: 1
mg
Add to list
Dulaglutide D545669
2024.04
Trulicity®
DE
319,00 € /mg
Select quantity:
Max: 12
Min: 1
Step: 1
Max: 12
Min: 1
Step: 1
mg
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Dulaglutide D550112
2023.12
Trulicity®
DE
319,00 € /mg
Select quantity:
Max: 16
Min: 1
Step: 1
Max: 16
Min: 1
Step: 1
mg
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Dupilumab 2F129A
2024.11
Dupixent®
LT
32,17 € /mg
Select quantity:
Max: 120
Min: 12
Step: 12
Max: 120
Min: 12
Step: 12
mg
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Durvalumab AACY
2021.10
Imfinzi®
DE
109,00 € /mg
Select quantity:
Max: 6
Min: 4
Step: 2
Max: 6
Min: 4
Step: 2
mg
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Eculizumab 1001027
2022.04
Soliris®
LT
186,75 € /mg
Select quantity:
Max: 40
Min: 4
Step: 4
Max: 40
Min: 4
Step: 4
mg
Add to list
Efgartigimod alfa
Date to be defined
Vyvgart®
DE
808,00 € /mg
Select quantity:
Max:
Min: 70
Step: 5
Max:
Min: 70
Step: 5
mg
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Elotuzumab 8065139
2026.10
Empliciti®
DE
33,00 €/mg
Max: 110
Min: 1
Step: 1
mg
Add to list
Elotuzumab ABQ7329
2022.09
Empliciti®
DE
49,33 € /mg
Select quantity:
Max: 60
Min: 12
Step: 6
Max: 60
Min: 12
Step: 6
mg
Add to list
Elotuzumab ACC0290
2024.02
Empliciti®
DE
49,33 € /mg
Select quantity:
Max: 60
Min: 12
Step: 6
Max: 60
Min: 12
Step: 6
mg
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Enfortumab Vedotin 3PA0169
2026.08
Padcev®
DE
259,00 €/mg
Max: 2
Min: 1
Step: 1
mg
Add to list
Enfortumab Vedotin 3PA0185
2026.12
Padcev®
DE
259,00 €/mg
Max: 5
Min: 1
Step: 1
mg
Add to list
Eptinezumab
Date to be defined
Vyepti®
DE
106,00 € /mg
Select quantity:
Max:
Min: 30
Step: 5
Max:
Min: 30
Step: 5
mg
Add to list
Erenumab
Date to be defined
Aimovig®
DE
70,00 € /mg
Select quantity:
Max:
Min: 31,5
Step: 3
Max:
Min: 31,5
Step: 3
mg
Add to list
Etanercept FL6599
2024.01
Enbrel®
DE
43,17 € /mg
Select quantity:
Max: 60
Min: 12
Step: 6
Max: 60
Min: 12
Step: 6
mg
Add to list
Etanercept S67398
2019.02
Enbrel®
DE
58,50 € /mg
Select quantity:
Max: 40
Min: 8
Step: 4
Max: 40
Min: 8
Step: 4
mg
Add to list
Etanercept T21782
2019.04
Enbrel®
DE
98,50 € /mg
Select quantity:
Max: 20
Min: 4
Step: 2
Max: 20
Min: 4
Step: 2
mg
Add to list
Etanercept T64915
2019.06
Enbrel®
DE
98,50 € /mg
Select quantity:
Max: 20
Min: 4
Step: 2
Max: 20
Min: 4
Step: 2
mg
Add to list
Etanercept W02981
2019.08
Enbrel®
DE
98,50 € /mg
Select quantity:
Max: 20
Min: 4
Step: 2
Max: 20
Min: 4
Step: 2
mg
Add to list
Etanercept W32559
2019.12
Enbrel®
DE
58,50 € /mg
Select quantity:
Max: 40
Min: 8
Step: 4
Max: 40
Min: 8
Step: 4
mg
Add to list
Etanercept W42283
2019.10
Enbrel®
DE
98,50 € /mg
Select quantity:
Max: 20
Min: 4
Step: 2
Max: 20
Min: 4
Step: 2
mg
Add to list
Etanercept X44248
2020.04
Enbrel®
DE
98,50 € /mg
Select quantity:
Max: 20
Min: 4
Step: 2
Max: 20
Min: 4
Step: 2
mg
Add to list
Evinacumab
Date to be defined
Evkeeza®
DE
1.088,00 € /mg
Select quantity:
Max:
Min: 8
Step: 1
Max:
Min: 8
Step: 1
mg
Add to list
Evolocumab 1152511A
2025.06
Repatha®
DE
122,00 €/mg
Max: 203
Min: 1
Step: 1
mg
Add to list
1 2 3
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Biosimilars as Aliquots​

Filters Sort results
Reset Apply
Product batch
Expiry date
Brand & Origin
Price
1. Select quantity range
2. Your quantity
Adalimumab 1120078A
2021.12
Amgevita®
DE
152,00 € /mg
Select quantity:
Max: 20
Min: 2
Step: 2
Max: 20
Min: 2
Step: 2
mg
Add to list
Adalimumab 1825216
2023.02
Hulio®
DE
152,00 € /mg
Select quantity:
Max: 20
Min: 2
Step: 2
Max: 20
Min: 2
Step: 2
mg
Add to list
Adalimumab 1909689A
2023.10
Hukyndra®
DE
152,00 € /mg
Select quantity:
Max: 20
Min: 2
Step: 2
Max: 20
Min: 2
Step: 2
mg
Add to list
Adalimumab 2LJP01T11
2024.02
Yuflyma®
DE
354,00 € /mg
Select quantity:
Max: 10
Min: 1
Step: 1
Max: 10
Min: 1
Step: 1
mg
Add to list
Adalimumab 2LJPO1T11
2024.02
Yuflyma®
DE
88,50 € /mg
Select quantity:
Max: 40
Min: 4
Step: 4
Max: 40
Min: 4
Step: 4
mg
Add to list
Adalimumab AU034994
2023.10
Idacio®
DE
177,50 € /mg
Select quantity:
Max: 20
Min: 2
Step: 2
Max: 20
Min: 2
Step: 2
mg
Add to list
Adalimumab GR226512
2023.10
Imraldi®
DE
152,00 € /mg
Select quantity:
Max: 20
Min: 2
Step: 2
Max: 20
Min: 2
Step: 2
mg
Add to list
Adalimumab MA8208
2024.06
Hyrimoz®
DE
152,00 € /mg
Select quantity:
Max: 20
Min: 2
Step: 2
Max: 20
Min: 2
Step: 2
mg
Add to list
Bevacizumab
Date to be defined
Abevmy®
DE
102,00 € /mg
Select quantity:
Max:
Min: 1
Step: 1
Max:
Min: 1
Step: 1
mg
Add to list
Bevacizumab
Date to be defined
Aybintio®
DE
102,00 € /mg
Select quantity:
Max:
Min: 20
Step: 2
Max:
Min: 20
Step: 2
mg
Add to list
Bevacizumab
Date to be defined
Vegzelma®
DE
102,00 € /mg
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2022.08
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2023.04
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2023.11
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2023.08
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2025.01
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2027.03
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2022.10
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2025.12
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2025.12
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2026.03
Rixathon®
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2025.01
Kanjinti®
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2026.08
Zercepac®
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2025.10
Ogivri®
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2026.09
Trazimera®
DE
61,00 €/mg
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Batch specific analytical data available

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Product Information

Here you will find the product information for the reference product.

NPlate® / Romiplostim Reference Product

Drug nameNplate®
INNRomiplostim
API typeFc-peptide fusion protein (peptibody)
Pharmacotherapeutic group
Antihaemorrhagics, other systemic haemostatics
ATC code
B02BX04
Target of antibody
TPO receptor (also known as cMpl)
General functionRomoplostim is indicated for the treatment of primary immune thrombocytopenia (ITP) in adult patients who are refractory to other treatments (e.g. corticosteroids, immunoglobulins). Nplate is indicated for the treatment of chronic primary immune thrombocytopenia (ITP) in paediatric patients one year of age and older who are refractory to other treatments (e.g. corticosteroids, immunoglobulins)
Short description
Pharmacodynamic properties
(Mechanism of action; Source EMA document)
Romiplostim is an Fc-peptide fusion protein (peptibody) that signals and activates intracellular transcriptional pathways via the TPO receptor (also known as cMpl) to increase platelet production. The peptibody molecule is comprised of a human immunoglobulin IgG1 Fc domain, with each single-chain subunit covalently linked at the C-terminus to a peptide chain containing 2 TPO receptor-binding domains. Romiplostim has no amino acid sequence homology to endogenous TPO. In pre-clinical and clinical trials no anti-romiplostim antibodies cross reacted with endogenous TPO.

The pharmacokinetics of romiplostim involved target-mediated disposition, which is presumably mediated by TPO receptors on platelets and other cells of the thrombopoietic lineage such as megakaryocytes.
Pharmacodynamic properties (Pharmacodynamic effects; Source EMA document)The pharmacokinetics of romiplostim involved target-mediated disposition, which is presumably mediated by TPO receptors on platelets and other cells of the thrombopoietic lineage such as megakaryocytes.

Due to the formation of neutralising antibodies pharmacodynamic effects of romiplostim in rats were often decreasing at prolonged duration of administration. Toxicokinetic studies showed no interaction of the antibodies with the measured concentrations.
Original license holder
Amgen Europe B.V.
Marketing authorisation numbers
EU/1/08/497/001
Marketing authorisation holder
Amgen Europe B.V. Minervum 7061 4817 ZK Breda The Netherlands
Name of the manufacturer of the biological active substance
Amgen Inc One Amgen Center Drive Thousand Oaks, CA 91320 USA
Name and address of the manufacturer(s) responsible for batch releaseAmgen Europe B.V. Minervum 7061 NL-4817 ZK Breda The Netherlands
Max shelf life
3 years
Storage conditions
2°C – 8°C
List of excipients
Mannitol (E421), Sucrose, L-histidine, Hydrochloric acid (for pH adjustment), Polysorbate 20

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