Therapeutic Romiplostim fusion protein from the original Nplate® commercial drug.
Product batch | Expiry date | Brand & Origin | Price | 1. Select quantity range | 2. Your quantity | |
---|---|---|---|---|---|---|
2023.02 |
Orencia® LT |
44,60 €
/mg
|
Select quantity: Max: 50
Min: 10
Step: 5
|
Max: 50
Min: 10
Step: 5
|
||
2025.05 |
Humira® DE |
112,50 €
/mg
|
Max: 4
Min: 1
Step: 1
|
|||
2018.09 |
Humira® DE |
113,00 €
/mg
|
Select quantity: Max: 16
Min: 4
Step: 4
|
Max: 16
Min: 4
Step: 4
|
||
2018.12 |
Humira® LV |
113,00 €
/mg
|
Select quantity: Max: 40
Min: 4
Step: 4
|
Max: 40
Min: 4
Step: 4
|
||
2019.03 |
Humira® DE |
113,00 €
/mg
|
Select quantity: Max: 40
Min: 4
Step: 4
|
Max: 40
Min: 4
Step: 4
|
||
2019.03 |
Humira® DE |
113,00 €
/mg
|
Select quantity: Max: 20
Min: 4
Step: 4
|
Max: 20
Min: 4
Step: 4
|
||
2019.07 |
Humira® LV |
113,00 €
/mg
|
Select quantity: Max: 32
Min: 4
Step: 4
|
Max: 32
Min: 4
Step: 4
|
||
Date to be defined |
Eylea® DE |
1.302,00 €
/mg
|
Select quantity: Max:
Min: 1
Step: 1
|
Max:
Min: 1
Step: 1
|
||
2023.01 |
Idelvion® DE |
20,80 €
/mg
|
Select quantity: Max: 125
Min: 25
Step: 25
|
Max: 125
Min: 25
Step: 25
|
||
2024.07 |
Proleukin® DE |
347,00 €
/mg
|
Select quantity: Max: 3
Min: 1
Step: 1
|
Max: 3
Min: 1
Step: 1
|
||
2026.01 |
Proleukin® DE |
260,00 €/mg
|
Max: 19
Min: 1
Step: 1
|
|||
2026.08 |
Lemtrada® DE |
1.862,00 €/mg
|
Max: 20
Min: 1
Step: 1
|
|||
2025.12 |
Myozyme® DE |
84,00 €/mg
|
Max: 315
Min: 1
Step: 1
|
|||
Date to be defined |
Praluent® DE |
36,00 €
/mg
|
Select quantity: Max:
Min: 60
Step: 6
|
Max:
Min: 60
Step: 6
|
||
2023.02 |
Actilyse® DE |
264,00 €
/mg
|
Select quantity: Max: 10
Min: 1
Step: 1
|
Max: 10
Min: 1
Step: 1
|
||
2027.04 |
Rybrevant® DE |
40,00 €/mg
|
Max: 50
Min: 1
Step: 1
|
|||
2026.11 |
Saphnelo® DE |
333,00 €
/mg
|
Select quantity: Max: 41
Min: 1
Step: 1
|
Max: 41
Min: 1
Step: 1
|
||
2022.03 |
Tecentriq® LT |
30,00 €
/mg
|
Select quantity: Max: 120
Min: 24
Step: 12
|
Max: 120
Min: 24
Step: 12
|
||
05/2026 |
Nexviadyme® DE |
1.099,00 €
/mg
|
Select quantity: Max: 18
Min: 1
Step: 1
|
Max: 18
Min: 1
Step: 1
|
||
2021.01 |
Bavencio® DE |
72,00 €
/mg
|
Select quantity: Max: 20
Min: 6
Step: 2
|
Max: 20
Min: 6
Step: 2
|
||
2025.01 |
Nulojix® |
37,00 €/mg
|
Max: 180
Min: 1
Step: 1
|
|||
Date to be defined |
Benlysta® DE |
59,00 €
/mg
|
Select quantity: Max:
Min: 32
Step: 4
|
Max:
Min: 32
Step: 4
|
||
Date to be defined |
Fasenra® DE |
504,00 €
/mg
|
Select quantity: Max:
Min: 9
Step: 1
|
Max:
Min: 9
Step: 1
|
||
2018.06 |
Avastin® DE |
106,00 €
/mg
|
Select quantity: Max: 20
Min: 4
Step: 2
|
Max: 20
Min: 4
Step: 2
|
||
2018.09 |
Avastin® DE |
106,00 €
/mg
|
Select quantity: Max: 20
Min: 4
Step: 2
|
Max: 20
Min: 4
Step: 2
|
||
2018.09 |
Avastin® DE |
106,00 €
/mg
|
Select quantity: Max: 20
Min: 4
Step: 2
|
Max: 20
Min: 4
Step: 2
|
||
2018.12 |
Avastin® DE |
106,00 €
/mg
|
Max: 20
Min: 4
Step: 2
|
|||
2019.03 |
Avastin® DE |
106,00 €
/mg
|
Select quantity: Max: 20
Min: 4
Step: 2
|
Max: 20
Min: 4
Step: 2
|
||
2019.08 |
Avastin® LV |
106,00 €
/mg
|
Select quantity: Max: 20
Min: 4
Step: 2
|
Max: 20
Min: 4
Step: 2
|
||
2019.10 |
Avastin® DE |
106,00 €
/mg
|
Select quantity: Max: 20
Min: 4
Step: 2
|
Max: 20
Min: 4
Step: 2
|
||
2021.03 |
Avastin® LT |
106,00 €
/mg
|
Select quantity: Max: 12
Min: 4
Step: 2
|
Max: 12
Min: 4
Step: 2
|
||
2017.09 |
Avastin® DE |
89,00 €
/mg
|
Select quantity: Max: 30
Min: 6
Step: 3
|
Max: 30
Min: 6
Step: 3
|
||
2018.03 |
Avastin® DE |
89,00 €
/mg
|
Select quantity: Max: 30
Min: 6
Step: 3
|
Max: 30
Min: 6
Step: 3
|
||
2024.07 |
Avastin® LT |
106,00 €
/mg
|
Select quantity: Max: 20
Min: 4
Step: 2
|
Max: 20
Min: 4
Step: 2
|
||
2027.03 |
Avastin® DE |
212,00 €
/mg
|
Select quantity: Max: 41
Min: 1
Step: 1
|
Max: 41
Min: 1
Step: 1
|
||
Date to be defined |
Zinplava® DE |
254,00 €
/mg
|
Select quantity: Max:
Min: 16
Step: 2
|
Max:
Min: 16
Step: 2
|
||
Date to be defined |
Bimzelx® DE |
73,00 €
/mg
|
Select quantity: Max:
Min: 64
Step: 8
|
Max:
Min: 64
Step: 8
|
||
2027.07 |
Blincyto® CH |
788,00 €/mg
|
Max: 8
Min: 1
Step: 1
|
|||
2027.09 |
Adcetris® DE |
370,00 €/mg
|
Max: 50
Min: 1
Step: 1
|
|||
2022.05 |
Kyntheum® DE |
42,14 €
/mg
|
Select quantity: Max: 70
Min: 14
Step: 7
|
Max: 70
Min: 14
Step: 7
|
||
Date to be defined |
Beovu® DE |
276,00 €
/mg
|
Select quantity: Max:
Min: 9,9
Step: 3
|
Max:
Min: 9,9
Step: 3
|
||
Date to be defined |
Crysvita® DE |
1.442,00 €
/mg
|
Select quantity: Max:
Min: 5
Step: 1
|
Max:
Min: 5
Step: 1
|
||
2025.07 |
Ilaris® DE |
1.884,00 €/mg
|
Max: 21
Min: 1
Step: 1
|
|||
2025.07 |
Ilaris® DE |
1.884,00 €/mg
|
Max: 23
Min: 1
Step: 1
|
|||
Date to be defined |
Libtayo® DE |
118,00 €
/mg
|
Select quantity: Max:
Min: 50
Step: 5
|
Max:
Min: 50
Step: 5
|
||
2022.09 |
Cimzia® DE |
34,25 €
/mg
|
Select quantity: Max: 72
Min: 16
Step: 8
|
Max: 72
Min: 16
Step: 8
|
||
2025.03 |
Cimzia® DE |
26,00 €/mg
|
Max: 256
Min: 1
Step: 1
|
|||
2019.11 |
Erbitux® DE |
98,50 €
/mg
|
Select quantity: Max: 20
Min: 6
Step: 2
|
Max: 20
Min: 6
Step: 2
|
||
2020.01 |
Erbitux® DE |
98,50 €
/mg
|
Select quantity: Max: 20
Min: 4
Step: 2
|
Max: 20
Min: 4
Step: 2
|
||
2021.05 |
Erbitux® DE |
98,50 €
/mg
|
Select quantity: Max: 20
Min: 4
Step: 2
|
Max: 20
Min: 4
Step: 2
|
||
2021.09 |
Erbitux® DE |
65,80 €
/mg
|
Select quantity: Max: 50
Min: 5
Step: 5
|
Max: 50
Min: 5
Step: 5
|
||
2021.11 |
Erbitux® DE |
98,50 €
/mg
|
Select quantity: Max: 20
Min: 4
Step: 2
|
Max: 20
Min: 4
Step: 2
|
||
Date to be defined |
Adakveo® DE |
167,00 €
/mg
|
Select quantity: Max:
Min: 18
Step: 2
|
Max:
Min: 18
Step: 2
|
||
2018.11 |
Darzalex® DE |
121,00 €
/mg
|
Select quantity: Max: 6
Min: 4
Step: 2
|
Max: 6
Min: 4
Step: 2
|
||
2019.05 |
Darzalex® DE |
121,00 €
/mg
|
Select quantity: Max: 34
Min: 4
Step: 4
|
Max: 34
Min: 4
Step: 4
|
||
2023.11 |
Darzalex® DE |
88,50 €
/mg
|
Select quantity: Max: 12
Min: 4
Step: 4
|
Max: 12
Min: 4
Step: 4
|
||
2024.11 |
Darzalex® DE |
88,50 €
/mg
|
Select quantity: Max: 40
Min: 4
Step: 4
|
Max: 40
Min: 4
Step: 4
|
||
2018.01 |
Darzalex® DE |
121,00 €
/mg
|
Select quantity: Max: 24
Min: 4
Step: 4
|
Max: 24
Min: 4
Step: 4
|
||
2018.04 |
Darzalex® DE |
101,30 €
/mg
|
Select quantity: Max: 30
Min: 6
Step: 3
|
Max: 30
Min: 6
Step: 3
|
||
2019.09 |
Darzalex® DE |
121,00 €
/mg
|
Select quantity: Max: 20
Min: 4
Step: 2
|
Max: 20
Min: 4
Step: 2
|
||
2021.01 |
Darzalex® DE |
121,00 €
/mg
|
Select quantity: Max: 20
Min: 4
Step: 2
|
Max: 20
Min: 4
Step: 2
|
||
2023.07 |
Darzalex® DE |
121,00 €
/mg
|
Select quantity: Max: 20
Min: 4
Step: 2
|
Max: 20
Min: 4
Step: 2
|
||
Date to be defined |
Xgeva® DE |
81,00 €
/mg
|
Select quantity: Max:
Min: 27
Step: 3
|
Max:
Min: 27
Step: 3
|
||
2018.11 |
Prolia® DE |
108,00 €
/mg
|
Select quantity: Max: 12
Min: 3
Step: 3
|
Max: 12
Min: 3
Step: 3
|
||
2019.07 |
Prolia® DE |
108,00 €
/mg
|
Select quantity: Max: 30
Min: 3
Step: 3
|
Max: 30
Min: 3
Step: 3
|
||
2019.10 |
Prolia® DE |
108,00 €
/mg
|
Select quantity: Max: 15
Min: 3
Step: 3
|
Max: 15
Min: 3
Step: 3
|
||
2020.04 |
Prolia® DE |
108,00 €
/mg
|
Select quantity: Max: 21
Min: 3
Step: 3
|
Max: 21
Min: 3
Step: 3
|
||
2020.09 |
Prolia® DE |
108,00 €
/mg
|
Select quantity: Max: 6
Min: 3
Step: 3
|
Max: 6
Min: 3
Step: 3
|
||
2021.01 |
Prolia® DE |
108,00 €
/mg
|
Select quantity: Max: 6
Min: 3
Step: 3
|
Max: 6
Min: 3
Step: 3
|
||
2022.06 |
Prolia® DE |
108,00 €
/mg
|
Select quantity: Max: 30
Min: 3
Step: 3
|
Max: 30
Min: 3
Step: 3
|
||
2022.10 |
Prolia® DE |
108,00 €
/mg
|
Select quantity: Max: 15
Min: 3
Step: 3
|
Max: 15
Min: 3
Step: 3
|
||
2023.12 |
Pulmozyme® DE |
188,00 €
/mg
|
Select quantity: Max: 3
Min: 1
Step: 1
|
Max: 3
Min: 1
Step: 1
|
||
2025.07 |
Jemperli® DE |
38,00 €/mg
|
Max: 500
Min: 1
Step: 1
|
|||
2025.10 |
Jemperli® IT |
105,00 €/mg
|
Max: 430
Min: 1
Step: 1
|
|||
2025.10 |
Jemperli® CH |
86,00 €/mg
|
Max: 430
Min: 1
Step: 1
|
|||
2026.03 |
Jemperli® USA |
180,00 €/mg
|
Max: 430
Min: 1
Step: 1
|
|||
2023.07 |
Trulicity® DE |
319,00 €
/mg
|
Select quantity: Max: 10
Min: 1
Step: 1
|
Max: 10
Min: 1
Step: 1
|
||
2024.04 |
Trulicity® DE |
319,00 €
/mg
|
Select quantity: Max: 12
Min: 1
Step: 1
|
Max: 12
Min: 1
Step: 1
|
||
2023.12 |
Trulicity® DE |
319,00 €
/mg
|
Select quantity: Max: 16
Min: 1
Step: 1
|
Max: 16
Min: 1
Step: 1
|
||
2024.11 |
Dupixent® LT |
32,17 €
/mg
|
Select quantity: Max: 120
Min: 12
Step: 12
|
Max: 120
Min: 12
Step: 12
|
||
2021.10 |
Imfinzi® DE |
109,00 €
/mg
|
Select quantity: Max: 6
Min: 4
Step: 2
|
Max: 6
Min: 4
Step: 2
|
||
2022.04 |
Soliris® LT |
186,75 €
/mg
|
Select quantity: Max: 40
Min: 4
Step: 4
|
Max: 40
Min: 4
Step: 4
|
||
Date to be defined |
Vyvgart® DE |
808,00 €
/mg
|
Select quantity: Max:
Min: 70
Step: 5
|
Max:
Min: 70
Step: 5
|
||
2026.10 |
Empliciti® DE |
33,00 €/mg
|
Max: 110
Min: 1
Step: 1
|
|||
2022.09 |
Empliciti® DE |
49,33 €
/mg
|
Select quantity: Max: 60
Min: 12
Step: 6
|
Max: 60
Min: 12
Step: 6
|
||
2024.02 |
Empliciti® DE |
49,33 €
/mg
|
Select quantity: Max: 60
Min: 12
Step: 6
|
Max: 60
Min: 12
Step: 6
|
||
2026.08 |
Padcev® DE |
259,00 €/mg
|
Max: 2
Min: 1
Step: 1
|
|||
2026.12 |
Padcev® DE |
259,00 €/mg
|
Max: 5
Min: 1
Step: 1
|
|||
Date to be defined |
Vyepti® DE |
106,00 €
/mg
|
Select quantity: Max:
Min: 30
Step: 5
|
Max:
Min: 30
Step: 5
|
||
Date to be defined |
Aimovig® DE |
70,00 €
/mg
|
Select quantity: Max:
Min: 31,5
Step: 3
|
Max:
Min: 31,5
Step: 3
|
||
2024.01 |
Enbrel® DE |
43,17 €
/mg
|
Select quantity: Max: 60
Min: 12
Step: 6
|
Max: 60
Min: 12
Step: 6
|
||
2019.02 |
Enbrel® DE |
58,50 €
/mg
|
Select quantity: Max: 40
Min: 8
Step: 4
|
Max: 40
Min: 8
Step: 4
|
||
2019.04 |
Enbrel® DE |
98,50 €
/mg
|
Select quantity: Max: 20
Min: 4
Step: 2
|
Max: 20
Min: 4
Step: 2
|
||
2019.06 |
Enbrel® DE |
98,50 €
/mg
|
Select quantity: Max: 20
Min: 4
Step: 2
|
Max: 20
Min: 4
Step: 2
|
||
2019.08 |
Enbrel® DE |
98,50 €
/mg
|
Select quantity: Max: 20
Min: 4
Step: 2
|
Max: 20
Min: 4
Step: 2
|
||
2019.12 |
Enbrel® DE |
58,50 €
/mg
|
Select quantity: Max: 40
Min: 8
Step: 4
|
Max: 40
Min: 8
Step: 4
|
||
2019.10 |
Enbrel® DE |
98,50 €
/mg
|
Select quantity: Max: 20
Min: 4
Step: 2
|
Max: 20
Min: 4
Step: 2
|
||
2020.04 |
Enbrel® DE |
98,50 €
/mg
|
Select quantity: Max: 20
Min: 4
Step: 2
|
Max: 20
Min: 4
Step: 2
|
||
Date to be defined |
Evkeeza® DE |
1.088,00 €
/mg
|
Select quantity: Max:
Min: 8
Step: 1
|
Max:
Min: 8
Step: 1
|
||
2025.06 |
Repatha® DE |
122,00 €/mg
|
Max: 203
Min: 1
Step: 1
|
Product batch | Expiry date | Brand & Origin | Price | 1. Select quantity range | 2. Your quantity | |
---|---|---|---|---|---|---|
2021.12 |
Amgevita® DE |
152,00 €
/mg
|
Select quantity: Max: 20
Min: 2
Step: 2
|
Max: 20
Min: 2
Step: 2
|
||
2023.02 |
Hulio® DE |
152,00 €
/mg
|
Select quantity: Max: 20
Min: 2
Step: 2
|
Max: 20
Min: 2
Step: 2
|
||
2023.10 |
Hukyndra® DE |
152,00 €
/mg
|
Select quantity: Max: 20
Min: 2
Step: 2
|
Max: 20
Min: 2
Step: 2
|
||
2024.02 |
Yuflyma® DE |
354,00 €
/mg
|
Select quantity: Max: 10
Min: 1
Step: 1
|
Max: 10
Min: 1
Step: 1
|
||
2024.02 |
Yuflyma® DE |
88,50 €
/mg
|
Select quantity: Max: 40
Min: 4
Step: 4
|
Max: 40
Min: 4
Step: 4
|
||
2023.10 |
Idacio® DE |
177,50 €
/mg
|
Select quantity: Max: 20
Min: 2
Step: 2
|
Max: 20
Min: 2
Step: 2
|
||
2023.10 |
Imraldi® DE |
152,00 €
/mg
|
Select quantity: Max: 20
Min: 2
Step: 2
|
Max: 20
Min: 2
Step: 2
|
||
2024.06 |
Hyrimoz® DE |
152,00 €
/mg
|
Select quantity: Max: 20
Min: 2
Step: 2
|
Max: 20
Min: 2
Step: 2
|
||
Date to be defined |
Abevmy® DE |
102,00 €
/mg
|
Select quantity: Max:
Min: 1
Step: 1
|
Max:
Min: 1
Step: 1
|
||
Date to be defined |
Aybintio® DE |
102,00 €
/mg
|
Select quantity: Max:
Min: 20
Step: 2
|
Max:
Min: 20
Step: 2
|
||
Date to be defined |
Vegzelma® DE |
102,00 €
/mg
|
Select quantity: Max:
Min: 1
Step: 1
|
Max:
Min: 1
Step: 1
|
||
Date to be defined |
Aybintio® |
102,00 €
/mg
|
Select quantity: Max:
Min: 11
Step: 1
|
Max:
Min: 11
Step: 1
|
||
Date to be defined |
Abevmy® |
107,00 €
/mg
|
Select quantity: Max:
Min: 11
Step: 1
|
Max:
Min: 11
Step: 1
|
||
Date to be defined |
Vegzelma® |
102,00 €
/mg
|
Select quantity: Max:
Min: 11
Step: 1
|
Max:
Min: 11
Step: 1
|
||
Date to be defined |
Epysqli® DE |
137,00 €
/mg
|
Select quantity: Max:
Min: 48
Step: 3
|
Max:
Min: 48
Step: 3
|
||
Date to be defined |
Epysqli® DE |
137,00 €
/mg
|
Select quantity: Max: 20
Min: 16
Step: 1
|
Max: 20
Min: 16
Step: 1
|
||
2022.08 |
Silapo® DE |
0,08 €
/mg
|
Select quantity: Max: 45000
Min: 5000
Step: 5000
|
Max: 45000
Min: 5000
Step: 5000
|
||
2023.04 |
Erelzi® DE |
68,00 €
/mg
|
Select quantity: Max: 40
Min: 8
Step: 4
|
Max: 40
Min: 8
Step: 4
|
||
2023.11 |
Benepali® DE |
68,00 €
/mg
|
Select quantity: Max: 27
Min: 1
Step: 1
|
Max: 27
Min: 1
Step: 1
|
||
2023.08 |
Nepexto® DE |
68,00 €
/mg
|
Select quantity: Max: 40
Min: 8
Step: 4
|
Max: 40
Min: 8
Step: 4
|
||
Date to be defined |
Remsima® DE |
120,00 €
/mg
|
Select quantity: Max:
Min: 20
Step: 2
|
Max:
Min: 20
Step: 2
|
||
2025.01 |
Flixabi® DE |
119,50 €
/mg
|
Select quantity: Max: 20
Min: 4
Step: 2
|
Max: 20
Min: 4
Step: 2
|
||
2027.03 |
Inflectra® |
90,00 €/mg
|
Max: 78
Min: 1
Step: 1
|
|||
2022.10 |
Zessly® DE |
120,50 €
/mg
|
Select quantity: Max: 20
Min: 4
Step: 2
|
Max: 20
Min: 4
Step: 2
|
||
Date to be defined |
Ranivisio® |
621,00 €
/mg
|
Select quantity: Max: 10
Min: 5
Step: 1
|
Max: 10
Min: 5
Step: 1
|
||
Date to be defined |
Ximluci® |
680,00 €
/mg
|
Select quantity: Max: 10
Min: 5
Step: 1
|
Max: 10
Min: 5
Step: 1
|
||
Date to be defined |
Byooviz® |
621,00 €
/mg
|
Select quantity: Max: 10
Min: 5
Step: 1
|
Max: 10
Min: 5
Step: 1
|
||
Date to be defined |
Truxima® |
117,00 €
/mg
|
Select quantity: Max:
Min: 10
Step: 1
|
Max:
Min: 10
Step: 1
|
||
2025.12 |
Ruxience® DE |
76,00 €/mg
|
Max: 80
Min: 1
Step: 1
|
|||
2025.12 |
Ruxience® DE |
202,00 €
/mg
|
Select quantity: Max: 40
Min: 1
Step: 1
|
Max: 40
Min: 1
Step: 1
|
||
2026.03 |
Rixathon® DE |
92,00 €/mg
|
Max: 74
Min: 1
Step: 1
|
|||
Date to be defined |
Max:
Min: 1
Step: 1
|
|||||
Date to be defined |
Ontruzant® DE |
62,00 €
/mg
|
Select quantity: Max:
Min: 42,042
Step: 6
|
Max:
Min: 42,042
Step: 6
|
||
Date to be defined |
Ontruzant® |
62,00 €
/mg
|
Select quantity: Max:
Min: 15
Step: 1
|
Max:
Min: 15
Step: 1
|
||
2025.01 |
Kanjinti® DE |
61,17 €
/mg
|
Select quantity: Max: 60
Min: 6
Step: 6
|
Max: 60
Min: 6
Step: 6
|
||
2026.08 |
Zercepac® DE |
52,00 €/mg
|
Max: 90
Min: 1
Step: 1
|
|||
2025.10 |
Ogivri® DE |
56,00 €/mg
|
Max: 72
Min: 1
Step: 1
|
|||
2026.09 |
Trazimera® DE |
61,00 €/mg
|
Max: 110
Min: 1
Step: 1
|
Evidentic’s analytical service includes a comprehensive array of methods to support the drug development process, including, for example, structure, aggregation, degree of isomerization and N-glycans identification of the active pharmaceutical ingredient (API).
Here you will find the product information for the reference product.
Drug name | Nplate® |
INN | Romiplostim |
API type | Fc-peptide fusion protein (peptibody) |
Pharmacotherapeutic group | Antihaemorrhagics, other systemic haemostatics |
ATC code | B02BX04 |
Target of antibody | TPO receptor (also known as cMpl) |
General function | Romoplostim is indicated for the treatment of primary immune thrombocytopenia (ITP) in adult patients who are refractory to other treatments (e.g. corticosteroids, immunoglobulins). Nplate is indicated for the treatment of chronic primary immune thrombocytopenia (ITP) in paediatric patients one year of age and older who are refractory to other treatments (e.g. corticosteroids, immunoglobulins) |
Short description | |
Pharmacodynamic properties (Mechanism of action; Source EMA document) | Romiplostim is an Fc-peptide fusion protein (peptibody) that signals and activates intracellular transcriptional pathways via the TPO receptor (also known as cMpl) to increase platelet production. The peptibody molecule is comprised of a human immunoglobulin IgG1 Fc domain, with each single-chain subunit covalently linked at the C-terminus to a peptide chain containing 2 TPO receptor-binding domains. Romiplostim has no amino acid sequence homology to endogenous TPO. In pre-clinical and clinical trials no anti-romiplostim antibodies cross reacted with endogenous TPO. The pharmacokinetics of romiplostim involved target-mediated disposition, which is presumably mediated by TPO receptors on platelets and other cells of the thrombopoietic lineage such as megakaryocytes. |
Pharmacodynamic properties (Pharmacodynamic effects; Source EMA document) | The pharmacokinetics of romiplostim involved target-mediated disposition, which is presumably mediated by TPO receptors on platelets and other cells of the thrombopoietic lineage such as megakaryocytes. Due to the formation of neutralising antibodies pharmacodynamic effects of romiplostim in rats were often decreasing at prolonged duration of administration. Toxicokinetic studies showed no interaction of the antibodies with the measured concentrations. |
Original license holder | Amgen Europe B.V. |
Marketing authorisation numbers | EU/1/08/497/001 |
Marketing authorisation holder | Amgen Europe B.V. Minervum 7061 4817 ZK Breda The Netherlands |
Name of the manufacturer of the biological active substance | Amgen Inc One Amgen Center Drive Thousand Oaks, CA 91320 USA |
Name and address of the manufacturer(s) responsible for batch release | Amgen Europe B.V. Minervum 7061 NL-4817 ZK Breda The Netherlands |
Max shelf life | 3 years |
Storage conditions | 2°C – 8°C |
List of excipients | Mannitol (E421), Sucrose, L-histidine, Hydrochloric acid (for pH adjustment), Polysorbate 20 |
Do you have any questions about the product, the ordering process or any other detail? Please contact us, we will reply within 24 hours.
At Evidentic, we deal with clinical-grade therapeutic molecules. Think of them as the building blocks for tomorrow’s groundbreaking treatments. These molecules are the active ingredients you’ll find in original drugs prescribed to patients, produced under the strictest quality and safety standards. They’ve also been therapeutically proven through rigorous clinical trials, meaning their effectiveness and safety for treating human diseases have been established. By offering researchers access to these essential tools, we’re fueling the fight for a healthier future.
Unlike some commercially available molecules, Evidentic’s clinical-grade therapeutics aren’t just research possibilities – they’re proven powerhouses! Derived from actual drugs used to treat human diseases, these molecules have already undergone rigorous testing and met the strictest safety and quality standards. This means researchers can focus their energy on groundbreaking discoveries, not questioning the reliability of their tools. With Evidentic, you get the confidence of knowing you’re working with the building blocks for real-world medical advancements.
If you struggle to source clinical-grade biologics you need for your research, Evidentic bridges the gap. We offer royalty-free research consumables (RUO-only) derived from original licensed drugs, giving you access to these critical research tools without the hassle.
But that’s not all. We understand the importance of batch variety in your research. That’s why we’ve built a comprehensive stock library, offering numerous batches of the same active pharmaceutical ingredient (API). This dedication to choice means you can find the exact batch that aligns with your specific research needs.
And because we’re constantly expanding our library, you can be sure we’re actively searching for new batches to add to your research arsenal. With Evidentic, unlock the power of readily available, high-quality research tools and accelerate your scientific breakthroughs.
Evidentic offers access to pharmaceuticals approved by the U.S. FDA (Food and Drug Administration) and/or the EMA (European Medicines Agency). This gives you access to a wider variety of molecules for your research, potentially shortening timelines and boosting the accuracy of your results. Compare EU and US molecules head-to-head, and accelerate your early drug development projects with access to these high-quality research tools. Contact us today to explore the possibilities!
Evidentic’s aliquots from approved pharnaceuticals can be used for analytical, in vitro research, typically executed in early drug development stage of drug discovery programs, like: