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Alemtuzumab

BATCH NUMBER: BW1652

2.277,00 

Therapeutic Alemtuzumab antibody from the original Lemtrada® commercial drug

In stock

Product specifications:​

  • Product Concentration 10 mg/mL
  • Volume per vial 50 µL
  • Quantity per vial 0,5 mg
  • Batch Number BW1652
  • Storage Temperature -80°C
Our products are for research use only. The “therapeutic expiration date” implies expiry date for patient adminstration and is not applicable to the shelf life of the aliquot. Aliquot storage at -86°C ensures fully functional molecules even after the mentioned expiry date

Product Information:

Evidentic offers repackaged finished pharmaceutical products (e.g RMP/RLD). We refer to the repackaged RMP/RLD products synonymously as drug aliquots or aRMP, or short: aliquots.

We offer batches of original drug aliquots in low-binding Eppendorf tubes for research use only. We provide license-free drug aliquots with long, short or even “negative shelf life” by storing the products at recommended temperatures (either 2-8°C or -80°C) and ensuring fully functional molecules for research purposes.

As ‘raw material’ for the production of drug aliquots, Evidentic sources RMP from the European (EU) market. As a licensed pharmaceutical wholesaler, Evidentic is committed to Good Distribution Practice (GDP) compliance with respect to the procurement, storage and shipment of RMP.
Drug aliquots are manufactured by repackaging RMP in a qualified laboratory. The aliquotation process is performed under a quality and manufacturing agreement between Evidentic and the contract manufacturer. Repackaging of RMP includes the following steps: opening the secondary and primary RMP containers and transferring the specified volumes of RMP into an Eppendorf 0.5 ml low-binding (or similar) tube. If the RMP is a lyophilized powder and not a highly concentrated solution, reconstitute the RMP according to the original manufacturer’s instructions and then aliquot as a highly concentrated solution.
For identification purposes, drug aliquots are labeled with the date of aliquoting, the original lot number of the RMP, the original expiration date of the RMP, the name of the active ingredient (INN), and a unique identification code.
Immediately after aliquoting, drug aliquots are stored at either 2-8 °C or -86 °C for long-term storage. All drug aliquots stored at 2-8 °C are transferred to -86 °C at least two weeks before the expiration date of the original RLD/RMP is reached. Further quality or functional testing are not performed on the drug aliquots.  

Class of molecule

Isotype

Host cells

Chinese Hamster Ovary (CHO) cells

Prepared from (Reference drug)​

Lemtrada®

Therapeutic Area

Therapeutic Indications

Mechanism of Action (MoA)

Alemtuzumab binds to CD52, a cell surface antigen present at high levels on T (CD3+) and B (CD19+) lymphocytes, and at lower levels on natural killer cells, monocytes, and macrophages. There is little or noCD52 detected on neutrophils, plasma cells, or bone marrow stem cells. Alemtuzumab acts throughantibody-dependent cellular cytolysis and complement-mediated lysis following cell surface binding to Tand B lymphocytes. The reduction in the level of circulating B and T cells by LEMTRADA and subsequent repopulation, mayreduce the potential for relapse, which ultimately delays disease progression.

Pharmacotherapeutic group​​

Immunosuppressants

List of Excipients​

Disodium phosphate dihydrate (E339)
Disodium edetate
Potassium chloride (E508)
Potassium dihydrogen phosphate (E340)
Polysorbate 80 (E433)
Sodium chloride

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Evidentic Support
+49 (0) 30 959 99 8831

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Shipping Information

To deliver aliquots to you before the Christmas break, please place your order one week before the following dates:

Thank you for your understanding, Your Evidentic team