In this section you can find updates and news about biological drugs research and development.
Biologic drugs approvals in 2021
Approvals of biologic drugs from EMA and FDA include new molecular entities (NMEs), expanded therapeutic indications, new dosage forms, novel formulations, and biosimilars. In the light of COVID-19, much of the biologic EUAs pertain to vaccines and anti-viral drugs against the SARS-CoV-2 virus. In addition, a number of breakthrough innovations have been approved for rare diseases, which is consistent with the current shift towards speciality drugs in the pharma industry.
News, Scientific Resources
Therapeutic antibodies against Omicron and new variants
The new variant of SARS CoV-2, B.1.1.529 Omicron, was designated as a variant of concern (VOC) by the World Health Organization (WHO). The virus's capacity to bind to ACE2 continues to be a key factor in its pathogenicity. Drugs for prophylactic therapy or preventing adverse effects are still under development. Even though Omicron is more transmissible than delta and resistant to most vaccinations and monoclonal antibodies, we still have at least two authorized monoclonal antibody treatments- Sotrovimab and Evusheld.
Merry Christmas and a Happy New Year
News, Press Releases
Bispecific Antibody Therapies in Cancer Immunology – Evidentic Scholarship 2021
Evidentic has launched a scholarship program in order to promote research projects of young researchers. This year we have awarded Ashley Reid, a PhD student from the Icahn School of Medicine at Mount Sinai, New York, United States.
Therapeutic Antibodies for COVID-19
Anti-virus monoclonal antibodies are currently considered one of the most effective therapeutic strategies to reduce viral replication and prevent mortality. Interestingly, experiments in animal models also show that neutralizing mAb therapies can potentially mitigate onward viral transmission.
Therapeutic mAbs, Analytics, News
Host Cell Protein analysis for biologics development
What are host cell proteins in biologic drugs?
News, Therapeutic mAbs
Critical Quality Attributes (CQAs) of Biologic Drugs
Defining critical quality attributes of biologics
Therapeutic mAbs, News, Scientific Resources
Therapeutic antibodies as Immune checkpoint inhibitors
Immunotherapy and Immune checkpoint inhibitors
Excipients: The inactive ingredients of biologics!
What are excipients for biologics?
Bispecific antibodies, News
Bispecific Antibodies: Coming-of-age in antibody therapeutics (Part 1 of 2)
Discovery of antibodies, also known as immunoglobulins, paved the way for the evolution of protein-based therapeutic molecules (biologics).